Detalhe da pesquisa
1.
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines.
Cell
; 184(21): 5432-5447.e16, 2021 10 14.
Artigo
Inglês
| MEDLINE | ID: mdl-34619077
2.
Adjuvanting a subunit COVID-19 vaccine to induce protective immunity.
Nature
; 594(7862): 253-258, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33873199
3.
The continued advance of vaccine adjuvants - 'we can work it out'.
Semin Immunol
; 50: 101426, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33257234
4.
Lipid-Based Nanoparticles for Delivery of Vaccine Adjuvants and Antigens: Toward Multicomponent Vaccines.
Mol Pharm
; 18(8): 2867-2888, 2021 08 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34264684
5.
Adjuvant effect of TLR7 agonist adsorbed on aluminum hydroxide (AS37): A phase I randomized, dose escalation study of an AS37-adjuvanted meningococcal C conjugated vaccine.
Clin Immunol
; 209: 108275, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31669193
6.
Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus.
Proc Natl Acad Sci U S A
; 112(12): 3680-5, 2015 Mar 24.
Artigo
Inglês
| MEDLINE | ID: mdl-25775551
7.
Vaccine adjuvant formulations: a pharmaceutical perspective.
Semin Immunol
; 25(2): 130-45, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23850011
8.
Rational Design of Adjuvant for Skin Delivery: Conjugation of Synthetic ß-Glucan Dectin-1 Agonist to Protein Antigen.
Mol Pharm
; 12(5): 1662-72, 2015 May 04.
Artigo
Inglês
| MEDLINE | ID: mdl-25867449
9.
A cationic nanoemulsion for the delivery of next-generation RNA vaccines.
Mol Ther
; 22(12): 2118-2129, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-25027661
10.
Nonviral delivery of self-amplifying RNA vaccines.
Proc Natl Acad Sci U S A
; 109(36): 14604-9, 2012 Sep 04.
Artigo
Inglês
| MEDLINE | ID: mdl-22908294
11.
Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88.
Proc Natl Acad Sci U S A
; 108(27): 11169-74, 2011 Jul 05.
Artigo
Inglês
| MEDLINE | ID: mdl-21690334
12.
The scientific journey of a novel adjuvant (AS37) from bench to bedside.
NPJ Vaccines
; 9(1): 26, 2024 Feb 08.
Artigo
Inglês
| MEDLINE | ID: mdl-38332005
13.
The vaccine adjuvant alum inhibits IL-12 by promoting PI3 kinase signaling while chitosan does not inhibit IL-12 and enhances Th1 and Th17 responses.
Eur J Immunol
; 42(10): 2709-19, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22777876
14.
Aluminum Adjuvants-'Back to the Future'.
Pharmaceutics
; 15(7)2023 Jul 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37514070
15.
A Self-Emulsified Adjuvant System Containing the Immune Potentiator Alpha Tocopherol Induces Higher Neutralizing Antibody Responses than a Squalene-Only Emulsion When Evaluated with a Recombinant Cytomegalovirus (CMV) Pentamer Antigen in Mice.
Pharmaceutics
; 15(1)2023 Jan 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36678865
16.
Maturation of Aluminium Adsorbed Antigens Contributes to the Creation of Homogeneous Vaccine Formulations.
Vaccines (Basel)
; 11(1)2023 Jan 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36680000
17.
Systems analysis of human responses to an aluminium hydroxide-adsorbed TLR7 agonist (AS37) adjuvanted vaccine reveals a dose-dependent and specific activation of the interferon-mediated antiviral response.
Vaccine
; 41(3): 724-734, 2023 01 16.
Artigo
Inglês
| MEDLINE | ID: mdl-36564274
18.
Extremely potent pan-sarbecovirus neutralizing antibodies generated by immunization of macaques with an AS03-adjuvanted monovalent subunit vaccine against SARS-CoV-2.
bioRxiv
; 2023 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-36711543
19.
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.
Sci Transl Med
; 15(695): eadg7404, 2023 05 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37163615
20.
Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome.
Proc Natl Acad Sci U S A
; 106(3): 870-5, 2009 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-19139407